References

diaendo

Сахарный диабет

Diabetes mellitus

2072-03512072-0378

Endocrinology research centre

10.14341/2072-0351-5521

diaendo-5521

Research Article

Статьи

Articles

Роль дистальной диабетической полинейропатии в развитии медиакальциноза у пациентов с сахарным диабетом

Role of distal diabetic polyneuropathy in the development of media calcification in patients with diabetesmellitus

Молитвословова

Наталья Александровна

Molitvoslovova

Natalya Alexandrovna

Галстян

Гагик Радикович

Galstyan

Gagik Radikovich

foot@endocrincentr.ru

ФГБУ Эндокринологический научный центр, МоскваEndocrinology Research Centre, Moscow

2012

15062012

152

№2 (2012)

6469

2012

Молитвословова Н.А., Галстян Г.Р.

Molitvoslovova N.A., Galstyan G.R.

Данная работа распространяется под лицензией Creative Commons Attribution 4.0.

This work is licensed under a Creative Commons Attribution 4.0 License.

https://www.dia-endojournals.ru/jour/article/view/5521

Кальцификация срединной оболочки артерий, или медиакальциноз часто встречается при диабете и ассоциирована с дис-тальной симметричной нейропатией. Артериальная кальцификация также осложняет хроническую болезнь почек и яв-ляется фактором риска кардиоваскулярной и общей смертности. Термин кальцификация не совсем точный, потому чтоморфологические изменения включают формирование костной ткани, т.е. оссификацию. Процессы комплексные, но тесносвязаны с процессами, вовлеченными в костный гомеостаз. Связь между дистальной симметричной нейропатией и каль-цификацией артериальной стенки указывает на то, что нейропатия может быть независимым фактором риска карди-оваскулярной смертности.

Arterial media calcification is a common finding in diabetes mellitus (DM) and is associated with distal symmetric neuropathy. Arterialcalcification also emerges as a complication of chronic kidney disease and is considered to be a risk factor for cardiovascular andgeneral morbidity. "Calcification" is actually not an accurate term, because morphologic alterations also include bone tissue formationor "ossification". Both processes are complex and exist in tight connection with bone homeostasis. Connection between distal symmetricneuropathy and arterial calcification suggests that neuropathy may be an independent risk factor for cardiovascular morbidity.

медиакальцинозсклероз Менкебергадистальная диабетическая полинейропатия

media calcificationMenckeberg's sclerosisdistal diabetic polyneuropathy

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The authors declare that there are no conflicts of interest present.