References

diaendo

Сахарный диабет

Diabetes mellitus

2072-03512072-0378

Endocrinology research centre

10.14341/2072-0351-5496

diaendo-5496

Research Article

Статьи

Articles

Новые показания к терапии эксенатидом у больных сахарным диабетом 2 типа с ожирением

New indications for exenatide therapy of type 2 diabetes mellitus

Викулова

Ольга Константиновна

Vikulova

Olga Konstantinovna

nephro@endocrincentr.ru

Шестакова

Марина Владимировна

Shestakova

Marina Vladimirovna

ФГУ Эндокринологический научный центр, МоскваEndocrinological Research Centre, Moscow

2010

15092010

133

№3 (2010)

98104

2010

Викулова О.К., Шестакова М.В.

Vikulova O.K., Shestakova M.V.

Данная работа распространяется под лицензией Creative Commons Attribution 4.0.

This work is licensed under a Creative Commons Attribution 4.0 License.

https://www.dia-endojournals.ru/jour/article/view/5496

Ожирение - один из ключевых факторов развития и прогрессирования сахарного диабета 2 типа (СД2), ассоциируемый с повышениемсердечно-сосудистого риска. Единственным классом сахароснижающих препаратов, который, помимо эффективной коррекции гипер-гликемии, обладает доказанным эффектом по снижению веса, являются миметики инкретинов. Эксенатид (Баета) - первый препаратэтого класса, одобренный к применению в монотерапии. В статье представлен детальный обзор материалов по профилю действия пре-парата и результаты клинических исследований, подтверждающих высокую эффективность Баеты при СД2, как в комбинированной,так и в монотерапии.

Obesity associated with the enhanced risk of cardiovascular disorders plays a key role in the evolvement and progression of type 2 diabetes mellitus(DM2). Incretin mimetics are the sole class of hypoglycemic agents that not only effectively correct hyperglycemia but also reduce body weight. Exenatide(Byetta) is the first drug of this class approved for the use as monotherapy. This paper presents a detailed review of the available data on thescope of exenatide effects and the results of its clinical studies that confirm high efficiency of Byetta used for both monotherapy and combined therapyof DM2.

сахарный диабет 2 типаожирениемиметики инкретиновэксенатидБаета

type 2 diabetes mellitusobesityincretin mimeticsexenatideByetta

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The authors declare that there are no conflicts of interest present.