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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">diaendo</journal-id><journal-title-group><journal-title xml:lang="ru">Сахарный диабет</journal-title><trans-title-group xml:lang="en"><trans-title>Diabetes mellitus</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2072-0351</issn><issn pub-type="epub">2072-0378</issn><publisher><publisher-name>Endocrinology research centre</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14341/2072-0351-5444</article-id><article-id custom-type="elpub" pub-id-type="custom">diaendo-5444</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Articles</subject></subj-group></article-categories><title-group><article-title>Перспективы терапии, направленной на восстановление пула бета-клеток,при сахарном диабете</article-title><trans-title-group xml:lang="en"><trans-title>Prospects for therapy aimed at restoring the beta-cell pool in patients with diabetes mellitus (review of the literature)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Петеркова</surname><given-names>Валентина Александровна</given-names></name><name name-style="western" xml:lang="en"><surname>Peterkova</surname><given-names>Valentina Alexandrovna</given-names></name></name-alternatives><email xlink:type="simple">-</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лаптев</surname><given-names>Дмитрий Никитич</given-names></name><name name-style="western" xml:lang="en"><surname>Laptev</surname><given-names>Dmitriy Nikitich</given-names></name></name-alternatives><email xlink:type="simple">laptevdn@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГУ Эндокринологический научный центр, Москва</institution></aff><aff xml:lang="en"><institution>Endocrinology Research Centre, Moscow</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2009</year></pub-date><pub-date pub-type="epub"><day>15</day><month>09</month><year>2009</year></pub-date><volume>12</volume><issue>3</issue><issue-title>№3 (2009)</issue-title><fpage>4</fpage><lpage>9</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Петеркова В.А., Лаптев Д.Н., 2009</copyright-statement><copyright-year>2009</copyright-year><copyright-holder xml:lang="ru">Петеркова В.А., Лаптев Д.Н.</copyright-holder><copyright-holder xml:lang="en">Peterkova V.A., Laptev D.N.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.dia-endojournals.ru/jour/article/view/5444">https://www.dia-endojournals.ru/jour/article/view/5444</self-uri><abstract><p>Обзор представляет результаты исследований возможностей, безопасности и перспективы регенеративной терапии, направленной навосстановление пула бета-клеток, при сахарном диабете (СД). Подробно проанализированы источники новых бета-клеток, механизмы регенерации, а также стимулирующие ее факторы.</p></abstract><trans-abstract xml:lang="en"><p>The authors review results of evaluation of possibility, safety and prospects of regenerative therapy aimed at restoring beta-cell pool in diabetes mellitus. A detailed analysis of sources of new beta-cells is presented, reparation mechanisms and factors contributing to regeneration are discussed.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>сахарный диабет</kwd><kwd>регенерация</kwd><kwd>бета-клетки</kwd></kwd-group><kwd-group xml:lang="en"><kwd>diabetes mellitus</kwd><kwd>regeneration</kwd><kwd>beta-cells</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Bonner-Weir S., Baxter L.A., Schuppin G.T., Smith F.E. 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