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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">diaendo</journal-id><journal-title-group><journal-title xml:lang="ru">Сахарный диабет</journal-title><trans-title-group xml:lang="en"><trans-title>Diabetes mellitus</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2072-0351</issn><issn pub-type="epub">2072-0378</issn><publisher><publisher-name>Endocrinology research centre</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14341/2072-0351-5393</article-id><article-id custom-type="elpub" pub-id-type="custom">diaendo-5393</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Articles</subject></subj-group></article-categories><title-group><article-title>Кардиоренальные взаимоотношения у больных сахарным диабетом 2 типа: новые данные исследования ADVANCE</article-title><trans-title-group xml:lang="en"><trans-title>Cardiorenal relationships in patients with type 2 diabetes mellitus: new data of the ADVANCE study</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шестакова</surname><given-names>Марина Владимировна</given-names></name><name name-style="western" xml:lang="en"><surname>Shestakova</surname><given-names>Marina Vladimirovna</given-names></name></name-alternatives><email xlink:type="simple">nephro@endocrincentr.ru</email></contrib></contrib-group><pub-date pub-type="collection"><year>2009</year></pub-date><pub-date pub-type="epub"><day>15</day><month>06</month><year>2009</year></pub-date><volume>12</volume><issue>2</issue><issue-title>№2 (2009)</issue-title><fpage>25</fpage><lpage>27</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Шестакова М.В., 2009</copyright-statement><copyright-year>2009</copyright-year><copyright-holder xml:lang="ru">Шестакова М.В.</copyright-holder><copyright-holder xml:lang="en">Shestakova M.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.dia-endojournals.ru/jour/article/view/5393">https://www.dia-endojournals.ru/jour/article/view/5393</self-uri><abstract><p>В исследовании ADVANCE прослеживается параллельное нарастание выраженности ренопротективного эффекта и предупреждения общей и сердечно-сосудистой смертности, что подтверждает гипотезу о взаимосвязи маркеров почечной и сердечно-сосудистой патологии. Исследование ADVANCE убедительно демонстрирует, что даже у пациентов СД2 старше 60 лет с высоким сердечно-сосудистым риском и длительным течением заболевания назначении в рутинной практике таких препаратов как диабетон?МВ и нолипрел форте безопасно и высокоэффективно, поскольку позволяет снизить риск развития и прогрессирования кардиоренального синдрома и сердечно-сосудистой смертности.</p></abstract><kwd-group xml:lang="ru"><kwd>сахарный диабет</kwd><kwd>диабетическая нефропатия</kwd><kwd>ишемическая болезнь сердца</kwd><kwd>артериальная гипертония</kwd></kwd-group><kwd-group xml:lang="en"><kwd>diabetes mellitus</kwd><kwd>diabetic nephropathy</kwd><kwd>coronary heart disease</kwd><kwd>arterial hypertension</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">US Renal Data System: USRDS 2007 Аnnual data report. 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