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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">diaendo</journal-id><journal-title-group><journal-title xml:lang="ru">Сахарный диабет</journal-title><trans-title-group xml:lang="en"><trans-title>Diabetes mellitus</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2072-0351</issn><issn pub-type="epub">2072-0378</issn><publisher><publisher-name>Endocrinology research centre</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14341/2072-0351-5391</article-id><article-id custom-type="elpub" pub-id-type="custom">diaendo-5391</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Articles</subject></subj-group></article-categories><title-group><article-title>Основные результаты ADVANCE: клиническая интерпретация для эндокринологов</article-title><trans-title-group xml:lang="en"><trans-title>Main results of the ADVANCE study: clinical interpretation for endocrinologists</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Залевская</surname><given-names>Алсу Гафуровна</given-names></name><name name-style="western" xml:lang="en"><surname>Zalevskya</surname><given-names>Alsu Gafurovna</given-names></name></name-alternatives><email xlink:type="simple">alsu-zalevskaya@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бабенко</surname><given-names>А Ю</given-names></name><name name-style="western" xml:lang="en"><surname>Babenko</surname><given-names>A Yu</given-names></name></name-alternatives><email xlink:type="simple">-</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Волкова</surname><given-names>А Р</given-names></name><name name-style="western" xml:lang="en"><surname>Volkova</surname><given-names>A R</given-names></name></name-alternatives><email xlink:type="simple">-</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>Санкт-Петербургский государственный медицинский университет им. акад. И.П. Павлова</institution></aff><pub-date pub-type="collection"><year>2009</year></pub-date><pub-date pub-type="epub"><day>15</day><month>06</month><year>2009</year></pub-date><volume>12</volume><issue>2</issue><issue-title>№2 (2009)</issue-title><fpage>14</fpage><lpage>17</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Залевская А.Г., Бабенко А.Ю., Волкова А.Р., 2009</copyright-statement><copyright-year>2009</copyright-year><copyright-holder xml:lang="ru">Залевская А.Г., Бабенко А.Ю., Волкова А.Р.</copyright-holder><copyright-holder xml:lang="en">Zalevskya A.G., Babenko A.Y., Volkova A.R.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.dia-endojournals.ru/jour/article/view/5391">https://www.dia-endojournals.ru/jour/article/view/5391</self-uri><abstract><p>Результаты ADVANCE приобретают особое значение. Могло показаться, что плохие новости исследования ACCORD могут поколебать уверенность специалистов в важности и необходимости достижения хорошего гликемического контроля при СД. Благодаря результатам исследования ADVANCE получены четкие доказательства того, что стратегия постепенного усиления сахароснижающей терапии с целью достижения целевого уровня гликированного гемоглобина (6,5%) безопасна и эффективна в отношении снижения риска поражения почек и макрососудистых исходов.</p></abstract><kwd-group xml:lang="ru"><kwd>сахарный диабет</kwd><kwd>факторы риска сердечно-сосудистых заболеваний</kwd><kwd>гликемия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>diabetes mellitus</kwd><kwd>risk factors of cardiovascular diseases</kwd><kwd>glycemia</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">International Diabetes Federation. // Diabetes Atlas 3-rd Ed.Brussels: International Diabetes Federation, 2006.</mixed-citation><mixed-citation xml:lang="en">International Diabetes Federation. // Diabetes Atlas 3-rd Ed.Brussels: International Diabetes Federation, 2006.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Anselmino M. et al. // Glucose lowering treatment in patients with coronary artery disease is prognostically important not only in established but also in newly detected Diabetes mellitus: a report from the Euro Heart Survey on Diabetes and the Heart. // Eur. 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