References

diaendo

Сахарный диабет

Diabetes mellitus

2072-03512072-0378

Endocrinology research centre

10.14341/2072-0351-3592

diaendo-3592

Research Article

Статьи

Articles

Нарушения углеводного обмена и коллатеральный кровоток в миокарде

Glycemic disorders and coronary collateral circulation

Старостин

Иван Васильевич

Starostin

Ivan Vasil'evich

ivs_01@bk.ru

Талицкий

Константин Александрович

Talitskiy

K A

Булкина

Ольга Самуиловна

Bulkina

O S

Карпов

Юрий Александрович

Karpov

Yury Alexandrovich

ФГБУ Российский кардиологический научно-производственный комплекс, МоскваRussian Cardiology Research and Production Center, Moscow

2013

15032013

161

№1 (2013)

1926

2013

Старостин И.В., Талицкий К.А., Булкина О.С., Карпов Ю.А.

Starostin I.V., Talitskiy K.A., Bulkina O.S., Karpov Y.A.

Данная работа распространяется под лицензией Creative Commons Attribution 4.0.

This work is licensed under a Creative Commons Attribution 4.0 License.

https://www.dia-endojournals.ru/jour/article/view/3592

Коллатеральный кровоток ? важнейший способ компенсации кровоснабжения ишемизированного миокарда, однако его эф- фективность подвержена выраженной внутри- и межвидовой вариабельности. Существуют экспериментальные и клини- ческие доказательства ассоциации неудовлетворительного коллатерального кровотока с нарушениями углеводного обмена. В обзоре рассматриваются основные механизмы нарушения формирования коллатерального кровотока при патологии угле- водного обмена, соотнесенные с этапами артериогенеза, а также дается оценка перспективам исследований в этом на- правлении.

Although collateral circulation is the essential means of perfusion for ischemized myocardium, its efficiency varies substantially within and between the species. There is both experimental and clinical evidence for association of glycemic disorders with inadequate col- lateral circulation. Current article reviews general mechanisms of collateral circulation failure due to such metabolic disturbances with regard for stages of arteriogenesis. We also highlight horizons of further studies in this field.

коллатеральный кровотокартериогенезсахарный диабетинсулинорезистентность

collateral circulationarteriogenesisdiabetes mellitusinsulin resistance

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The authors declare that there are no conflicts of interest present.