diaendoСахарный диабетDiabetes mellitus2072-03512072-0378Endocrinology research centre10.14341/DM13122diaendo-13122Research ArticleОбзорыReviewСиндром пищевых эксцессов: эпидемиологические, клинико-патогенетические и терапевтические аспектыBinge eating disorder: epidemiological, clinical, pathophysiological, and treatment aspectshttps://orcid.org/0000-0002-3328-2812СтаростинаЕ. Г.StarostinaE. G.

Старостина Елена Георгиевна - д.м.н., профессор; ResearcherID: C-9409-2014; Scopus Author ID: 7003980023.

129110, Москва, ул. Щепкина, д. 61/2

Elena G. Starostina - MD, PhD, Professor; ResearcherID: C-9409-2014; Scopus Author ID: 7003980023.

61/2 Schepkina street, 129110 Moscow

elena.starostina@rambler.ruhttps://orcid.org/0009-0008-6263-3790АнанянМ. В.AnanyanM. V.

Ананян Мариам Валерьевна – аспирант.

Москва

Mariam V. Ananyan - PhD Student.

Moscow

aymariam@mail.ruМосковский областной научно-исследовательский клинический институт им. М.Ф. ВладимирскогоРоссияMoscow Regional Clinical and Research CentreRussian Federation2024190320242718192Copyright © Старостина Е.Г., Ананян М.В., 20242024Старостина Е.Г., Ананян М.В.Starostina E.G., Ananyan M.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.dia-endojournals.ru/jour/article/view/13122

Синдром пищевых эксцессов (СПЭ) — самый частый вид расстройств приема пищи, встречающийся в эндокринологической практике: им страдают от 5 до 66% пациентов с ожирением, обращающихся к врачу для снижения массы тела, 10–25% пациентов с сахарным диабетом 2 типа (СД2) и более 70% больных СД2 с морбидным ожирением. СПЭ серьезно затрудняет эффективное лечение СД2 и ожирения, оставаясь в большинстве случаев не диагностированным и не леченным. В обзоре обсуждаются диагностические критерии СПЭ и их эволюция за последние три десятилетия, нейробиохимические, генетические и психологические компоненты его патогенеза, а также возможная роль СПЭ как нового фактора риска СД2. Проанализированы доступные для эндокринолога варианты медикаментозной терапии, включая перспективы применения агонистов рецепторов глюкагоноподобного пептида-1.

Binge eating disorder (BED) is the most prevalent type of eating disorders encountered in endocrinological practice, with 5 to 66% of obesity patients seeking for losing weight, 10 to 25% of patients with Type 2 diabetes mellitus, and above 70% of Type 2 patients with morbid obesity having BED. BED can seriously challenge the treatment for Type 2 diabetes and obesity, but remains underdiagnosed and undertreated in most cases. The review discussed diagnostic criteria of BED and their evolution during the last three decades, as well as neurochemical, genetic, and psychological components of its pathophysiology and potential role of BED as a new risk factor for Type 2 diabetes. We have also analyzed medical treatments available for an endocrinologist, including potential use of agonists of glucagone-like peptide 1 receptors.

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Int J Eat Disord. 2019; 52(2): 153–158. https://doi.org/10.1002/eat.23002Министерство здравоохранения Российской Федерации. Письмо от 1 июня 2023 г. N 15-5/3045153-13170. Доступно на https://rulaws.ru/acts/Pismo-Minzdrava-Rossii-ot-01.06.2023-N-15-5_3045153-13170/Министерство здравоохранения Российской Федерации. Письмо от 1 июня 2023 г. N 15-5/3045153-13170. Доступно на https://rulaws.ru/acts/Pismo-Minzdrava-Rossii-ot-01.06.2023-N-15-5_3045153-13170/

The authors declare that there are no conflicts of interest present.